Maryam Rahbaran

M.Sc. Student 
Medical Physics Unit
Department of Oncology

Novel Brachytherapy Technology

Bio

Maryam is a summer co-op student in Dr. Enger’s lab, working remotely from Vancouver, BC. Maryam will be graduating with her B.Sc. in Spring 2022 with the goal of continuing studies in Medical Physics at the graduate level. In her free time, she enjoys painting and creative writing.

Current Projects

Development of a Software Package for Monte Carlo-based Intravascular Brachytherapy Dosimetry
Each year, cardiovascular diseases claim the lives of more people in the United States than chronic lung disease and cancer combined. The most common form of cardiovascular disease is coronary artery disease (CAD). CAD is commonly treated with a percutaneous transluminal coronary angioplasty (PTCA), where a small deflated balloon is led to a blocked section of an artery, then is inflated to create an opening. Typically drug-eluting stents (DES) are left behind to keep the artery open and slowly deliver medication to prevent in-stent restenosis (ISR). ISR is caused by metal stents putting stress on the arterial wall resulting in tissue damage and thus neointimal hyperplasia. Plaque is overproduced, which may result in narrowing the opening once again. Intravascular brachytherapy (IVBT) was the main course of treatment when only bare metal stents were used before DES were introduced in the early 90’s. IVBT consists of beta-emitting radionuclide seeds inside of a catheter-based device delivering radiation to stop neointimal hyperplasia at the lesion site. Treatment planning for IVBT is limited as AAPM task group 43, 60, and 149 base dose prescription off of dosimetry in a homogenous water phantom. However, Monte-Carlo based studies have shown that heterogeneities such as the guidewire of the IVBT device, calcification, and metal stents significantly attenuate dose. This project aims to simulate how much dose is attenuated due to these heterogeneities, how stent placement affects dose attenuation, and the angular dependence of dose distribution. 

2022

Rahbaran, Maryam

Graduate Excellence Award Award

from in 2022.

Abstract | BibTeX

Rahbaran, Maryam; Kalinowski, Jonathan; Tsui, James Man Git; DeCunha, Joseph; Enger, Shirin A.

Monte-Carlo Based Simulations of the Uncertainties in Clinical Water-Based Intravascular Brachytherapy Dosimetry Presentation

11.04.2022.

Abstract | BibTeX